Abstract 64: Synthetic Mesh versus Acellular Dermal Matrix for Oncologic Chest Wall Reconstruction: A Comparative Analysis

RESULTS: The decision tree shows the associated probabilities, QALYs and costs for each clinical outcome arising from either the LVOS arm or the SSIR arm. An ICUR of $644/QALY favoring LVOS was calculated based off of its clinical-effectiveness gain of 7.11 QALY at an additional cost of $4,579.43 (partly due to the additional costs of radiation treatment and the bilateral operation needed for LVOS compared to no radiation and unilateral surgery for SSIR). This proved that LVOS is a cost-effective surgical option given that a surgical approach is deemed cost-effective if its ICUR is less than $50,000/QALY. One-way sensitivity analyses underscored the degree by which LVOS was costeffective. For example, LVOS became cost-ineffective when a successful LVOS cost more than $50,000. Similarly, probabilistic sensitivity analysis using Monte-Carlo simulation showed that even with varying multiple variables at once, results tended to favor our conclusion supporting the costeffectiveness of LVOS.